---
name: AXOlabs
slug: axolabs
site: both
website_domain: axolabs.com
summary: Integrated CRO and CDMO specializing in nucleic acid therapeutics (ASOs, siRNA, sgRNA, aptamers) from lead identification through GMP manufacturing, with dual-site facilities in Petaluma, USA and Berlin, Germany. Headquartered in Petaluma, United States.
tagline: Nucleic acid therapeutics CRO and CDMO from discovery to GMP manufacturing.
founded_year: 
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: US
tier2_domain_verified: false
updated_at: 2026-10-19T07:02:40.643Z
services_count: 13
modalities_count: 1
indications_count: 0
locations_count: 3
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# AXOlabs

Nucleic acid therapeutics CRO and CDMO from discovery to GMP manufacturing.

Listed on cdmo.directory.

## Summary

Integrated CRO and CDMO specializing in nucleic acid therapeutics (ASOs, siRNA, sgRNA, aptamers) from lead identification through GMP manufacturing, with dual-site facilities in Petaluma, USA and Berlin, Germany. Headquartered in Petaluma, United States.

## At a glance

- HQ country: US

## Services

- Bioinformatics & Data Science
- High-Throughput Screening
- Target Identification & Validation
- Discovery Research
- GLP Toxicology
- In Vivo PK / PD Studies
- Bioanalysis
- LC-MS Bioanalysis (Small Molecule)
- In Vitro Pharmacology
- Oligonucleotide Manufacturing
- Process Development
- CMC Analytical Development
- Technology Transfer

## Modalities

- Oligonucleotide

## Locations

- Petaluma, Petaluma, California, USA
- Berlin, Berlin, Berlin, Germany
- Kulmbach, Kulmbach, Bavaria, Germany

## Certifications

- GLP; Identifier: Statement of GLP Compliance (06 Dec 2024); Source: https://axolabs.com/
- GMP; Identifier: Certificate of GMP Compliance (Regierung von Oberfranken, 14 Oct 2024); Source: https://axolabs.com/

## Long description

Axolabs provides integrated contract research and manufacturing services for nucleic acid therapeutics, spanning discovery through commercial-scale GMP production.

## CRO Services

**Discovery:** Lead identification and chemistry optimization using bioinformatics-driven design, proprietary sequence selection algorithms, high-throughput screening, and RNA-Seq-based off-target analysis. The Kulmbach facility houses a deep bioinformatics platform and multiplex screening infrastructure.

**Preclinical:** Preclinical safety, pharmacokinetics, and biodistribution studies; early synthesis and process development to support IND/CTA submissions. Capabilities include solid-phase oligonucleotide synthesis and conjugates, GLP-compliant bioanalysis (proprietary PNA assay), LC-MS/MS assays, and advanced cell-based functional testing.

## CDMO Services

**Preclinical Manufacturing:** Non-GMP to GMP manufacturing, process development, and synthesis scale-up for toxicology studies. Synthesis of chemically modified oligonucleotides and conjugates with advanced in-process controls and comprehensive impurity profiling.

**Clinical & Commercial GMP:** GMP-compliant production of nucleic acid therapeutics (ASOs, siRNA, sgRNA, aptamers, bioconjugates) for clinical trial phases I–III and initial commercial supply. Dual-site, globally integrated facilities equipped with Cytiva OligoPilot™, OligoProcess™, and Asahi Kasei Bioprocess (AKB THESYS™) platforms. Comprehensive analytics, in-line process monitoring, and regulatory-compliant validation.

## Related companies

- [atdbio](/companies/atdbio) (Oligonucleotide Manufacturing, Process Development) — [Compare](/compare/atdbio/axolabs)
- [CPC Scientific](/companies/cpcscientific) (Oligonucleotide Manufacturing, Process Development) — [Compare](/compare/axolabs/cpcscientific)
- [ChemGenes](/companies/chemgenes) (Oligonucleotide Manufacturing, CMC Analytical Development) — [Compare](/compare/axolabs/chemgenes)
- [Nuvisan](/companies/nuvisan) (Bioinformatics & Data Science, High-Throughput Screening) — [Compare](/compare/axolabs/nuvisan)
- [Biospring](/companies/biospring) (Oligonucleotide Manufacturing, Process Development) — [Compare](/compare/axolabs/biospring)
- [Bachem](/companies/bachem) (Oligonucleotide Manufacturing, Process Development) — [Compare](/compare/axolabs/bachem)
- [PI Health Sciences](/companies/pihealthsciences) (High-Throughput Screening, Target Identification & Validation) — [Compare](/compare/axolabs/pihealthsciences)
- [Sinopep-Allsino Biopharmaceutical Co., Ltd.](/companies/sinopep) (Oligonucleotide Manufacturing, Process Development) — [Compare](/compare/axolabs/sinopep)

_Profile last updated: 2026-10-19T07:02:40.643Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.