Bio-Synthesis, Inc.

Bio-Synthesis, Inc. describes itself as an integrated CDMO platform that brings nucleic acid synthesis, peptide manufacturing, bioconjugation, molecular biology, analytical testing, and scale-up support within one scientific organization.

Oligonucleotide capabilities

• Custom DNA, RNA, PNA, Morpholino, siRNA, and ASO synthesis, with extensive modification, conjugation, purification, and scale-up options.
• Complex oligonucleotide and conjugate work, including peptide–oligo conjugates, GalNAc and targeting ligands, lipid conjugates, and specialty linkers.
• Oligo process development, analytical method development, release QC, and stability studies.

Peptide and conjugation capabilities

• Custom peptide synthesis from research through development, including difficult sequences, advanced modifications, purification, and analytical characterization.
• Project-specific conjugation of oligonucleotides, peptides, proteins, antibodies, lipids, fluorophores, targeting ligands, polymers, and small molecules.

Other services

• Custom cloning, gene synthesis, mutagenesis, and sequencing support.
• Ready-to-order research reagents for life-science workflows, alongside fee-for-service development and manufacturing work.

The company states it can help evaluate manufacturability and develop a practical synthesis strategy for programs with unusual modifications, multiple conjugations, or demanding scale-up requirements.