---
name: Icosagen
slug: icosagen
site: both
website_domain: icosagen.com
summary: Icosagen is an integrated CRDMO (Contract Research, Development & Manufacturing Organization) specializing in antibody discovery, protein production, cell line development, and GMP manufacturing for biologics programs from discovery through commercial scale. Headquartered in Estonia.
tagline: Integrated CRO and CDMO services for antibody and protein biologics from discovery to GMP manufacturing.
founded_year: 
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: EE
tier2_domain_verified: false
updated_at: 2026-08-23T07:03:22.161Z
services_count: 9
modalities_count: 3
indications_count: 0
locations_count: 1
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# Icosagen

Integrated CRO and CDMO services for antibody and protein biologics from discovery to GMP manufacturing.

Listed on cdmo.directory.

## Summary

Icosagen is an integrated CRDMO (Contract Research, Development & Manufacturing Organization) specializing in antibody discovery, protein production, cell line development, and GMP manufacturing for biologics programs from discovery through commercial scale. Headquartered in Estonia.

## At a glance

- HQ country: EE

## Services

- Cell-Line Development
- Recombinant Protein Manufacturing
- Process Development
- Upstream Processing
- Downstream Processing
- CMC Analytical Development
- ADC (Antibody-Drug Conjugate) Manufacturing
- Bioconjugation Services
- Biologics Development & Manufacturing

## Modalities

- Biologics (Monoclonal Antibodies)
- Biologics (Other)
- Antibody-Drug Conjugate (ADC)

## Locations

- Headquarters, Estonia

## Long description

## Overview

Icosagen is an end-to-end Contract Research, Development & Manufacturing Organization (CRDMO) that bridges CRO and CDMO capabilities under one roof. The company specializes in antibody and protein biologics solutions, supporting clients across the full lifecycle from early discovery through GMP manufacturing.

## Core Service Areas

**Antibody Discovery & Development**
- Early antibody developability assessment
- Antibody discovery (phage display, B-cell panning, hybridoma sequencing, immunization)
- Antibody development and engineering (bispecific antibody engineering, affinity maturation, humanization)
- Antibody-drug conjugate (ADC) development and manufacturing

**Protein Production**
- Transient expression systems
- Bispecific antibodies
- Membrane protein expression
- ADCC enhancement
- Protein purification and analytics

**Cell Line Development**
- Cell line development services
- Cell-based assays

**Process Development & Manufacturing**
- Upstream process development
- Downstream process development
- GMP manufacturing capabilities
- Food microbiology testing

## Proprietary Technologies

Icosagen operates proprietary platforms including HybriFree Technology, QMCF Technology, and IcoCell® Technology to support client programs.

## Client Base

The company has partnered with numerous biotech and pharma organizations globally, with demonstrated expertise in supporting pre-clinical antibody/protein production, characterization, and lead optimization phases. Client testimonials highlight technical expertise in complex protein expression, reliability, quick turnaround times, and transparent communication.

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- [Creative Biolabs](/companies/creativebiolabs) (Cell-Line Development, Recombinant Protein Manufacturing) — [Compare](/compare/creativebiolabs/icosagen)
- [KBI Biopharma, Inc.](/companies/kbibiopharma) (Cell-Line Development, Recombinant Protein Manufacturing) — [Compare](/compare/icosagen/kbibiopharma)
- [Cytovance Biologics](/companies/cytovance-biologics) (Cell-Line Development, Recombinant Protein Manufacturing) — [Compare](/compare/cytovance-biologics/icosagen)

_Profile last updated: 2026-08-23T07:03:22.161Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.