---
name: Micromacinazione
slug: micromacinazione
site: cdmo
website_domain: micromacinazione.com
summary: Swiss-based CDMO specializing in particle engineering and micronization with over 50 years of experience. Offers micronization, milling, spray drying, solid-state characterization, and complementary processing services (classification, blending, cryogenic, co-micronization, conditioning) for APIs, HPAPIs, controlled substances, and excipients from early development to commercial GMP scale. Headquartered in Monteggio, Switzerland.
tagline: Specialized particle engineering CDMO with 50+ years of micronization expertise and dual-source GMP capacity.
founded_year: 1970
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: CH
tier2_domain_verified: false
updated_at: 2026-08-23T07:03:28.020Z
services_count: 6
modalities_count: 1
indications_count: 0
locations_count: 2
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# Micromacinazione

Specialized particle engineering CDMO with 50+ years of micronization expertise and dual-source GMP capacity.

Listed on cdmo.directory.

## Summary

Swiss-based CDMO specializing in particle engineering and micronization with over 50 years of experience. Offers micronization, milling, spray drying, solid-state characterization, and complementary processing services (classification, blending, cryogenic, co-micronization, conditioning) for APIs, HPAPIs, controlled substances, and excipients from early development to commercial GMP scale. Headquartered in Monteggio, Switzerland.

## At a glance

- Founded: 1970
- HQ country: CH

## Services

- Process Development
- CMC Analytical Development
- Solid-State Chemistry & Polymorph Screening
- HPAPI Manufacturing (High-Potency)
- API Synthesis & Manufacturing
- Small Molecule Development & Manufacturing

## Modalities

- Small Molecule

## Locations

- Headquarters, Monteggio, Ticino, Switzerland
- US Operations, Quakertown, Pennsylvania, USA

## Certifications

- GMP; Identifier: GMP-inspected production facilities; Source: https://micromacinazione.com/

## Long description

## Overview

Micromacinazione is a Swiss-based pharmaceutical CDMO headquartered in Monteggio, Switzerland, with a global presence through partnership with Microsize in Quakertown, Pennsylvania. The company specializes in particle engineering and micronization, leveraging over 50 years of technical expertise and operational infrastructure.

## Core Services

**Particle Engineering:**
- Micronization for poorly soluble compounds to improve dissolution, absorption, and clinical performance
- Milling for size reduction and particle optimization
- Spray drying for powder formulation development

**Complementary Processing:**
- Classification: Dynamic cyclone classification for precise aerodynamic fractions, essential for pulmonary delivery
- Blending: Planetary mixing for uniform API-excipient dry powder blends
- Cryogenic processing: Liquid nitrogen cooling for thermolabile or ductile compounds
- Co-micronization: Simultaneous jet milling of API and functional excipient for particle-level interaction
- Conditioning: Controlled humidity and temperature exposure for amorphous surface stabilization

**Analytics:**
- Particle characterization
- Solid-state characterization

## Product Categories

The company serves APIs/HPAPIs, excipients, controlled substances, and specialty chemicals across development and commercial scales.

## Infrastructure & Capabilities

- One dedicated R&D laboratory
- Three fully GMP-inspected production buildings
- Processing capacity from gram-scale feasibility to large commercial batches
- High-containment expertise for potent and controlled substances
- Dual-source capability across Switzerland and USA for supply continuity
- Global integration within a wider network of strategic partners for equipment innovation and technical solutions

## Differentiation

The company positions itself as a specialized particle engineering partner (not a generalist CDMO) built on three pillars: Science Vanguard, Partnership by Design, and Redundancy. The team brings decades of particle engineering expertise, with operational capacity among the largest in Europe.

## Related companies

- [Divi's Laboratories](/companies/divislabs) (Process Development, CMC Analytical Development) — [Compare](/compare/divislabs/micromacinazione)
- [Roquette Pharma Solutions](/companies/roquette) (CMC Analytical Development, API Synthesis & Manufacturing) — [Compare](/compare/micromacinazione/roquette)
- [CMC Pharmaceuticals, Inc.](/companies/cmcpharm) (Process Development, CMC Analytical Development) — [Compare](/compare/cmcpharm/micromacinazione)
- [Axplora](/companies/axplora) (Process Development, CMC Analytical Development) — [Compare](/compare/axplora/micromacinazione)
- [Laurus Labs](/companies/lauruslabs) (Process Development, CMC Analytical Development) — [Compare](/compare/lauruslabs/micromacinazione)
- [SEQENS](/companies/seqens) (Process Development, CMC Analytical Development) — [Compare](/compare/micromacinazione/seqens)
- [Sterling Pharma Solutions](/companies/sterlingpharmasolutions) (Process Development, CMC Analytical Development) — [Compare](/compare/micromacinazione/sterlingpharmasolutions)
- [PharmaBlock](/companies/pharmablock) (Process Development, CMC Analytical Development) — [Compare](/compare/micromacinazione/pharmablock)

_Profile last updated: 2026-08-23T07:03:28.020Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.