---
name: Northern RNA
slug: northernrna
site: cdmo
website_domain: northernrna.com
summary: Calgary-based manufacturer of GMP-grade linear plasmid DNA and mRNA, with custom Co Cap analogs and LNP lipid formulation for client programs. Also offers microbial cell banking, chemical manufacturing, development services, and analytical and stability testing. Headquartered in Calgary, Canada.
tagline: End-to-end nucleic acid manufacturing: GMP plasmid DNA, mRNA, Co Cap analogs, and LNP formulation
founded_year: 
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: CA
tier2_domain_verified: false
updated_at: 2026-10-26T07:03:54.484Z
services_count: 6
modalities_count: 2
indications_count: 0
locations_count: 1
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# Northern RNA

End-to-end nucleic acid manufacturing: GMP plasmid DNA, mRNA, Co Cap analogs, and LNP formulation

Listed on cdmo.directory.

## Summary

Calgary-based manufacturer of GMP-grade linear plasmid DNA and mRNA, with custom Co Cap analogs and LNP lipid formulation for client programs. Also offers microbial cell banking, chemical manufacturing, development services, and analytical and stability testing. Headquartered in Calgary, Canada.

## At a glance

- HQ country: CA

## Services

- mRNA Manufacturing
- Lipid Nanoparticle (LNP) Formulation
- Formulation Development
- Process Development
- Analytical Method Development & Validation
- Stability Testing & Storage

## Modalities

- mRNA
- Vaccine

## Locations

- Headquarters, Calgary, Alberta, Canada

## Long description

## Overview

Northern RNA describes itself as an end-to-end supplier of nucleic acid products, including mRNA and DNA. The company states that its scientists have decades of experience manufacturing high-quality nucleic acids, raw materials, and drug substances and products.

## Services

- **Biomanufacturing** and **plasmid DNA production**, including complex constructs with multiple or tandem repeats, GC-rich regions, and highly structured regions.
- **mRNA production**, covering synthesis, purification, and formulation.
- **Co Cap analogs** produced off-the-shelf or custom-designed at various scales, with a dedicated team for lipid production and formulation.
- **Formulation** and **LNP formulation**.
- **Microbial cell banking** and **chemical manufacturing**.
- **R&D development services** and **analytical and stability testing**.
- **Storage services** and cold chain distribution.

## Differentiation

The company says it uses proprietary manufacturing and analytical approaches and provides traceable, high-quality documentation. It lists GMP-grade linear plasmid DNA and GMP-grade mRNA among its products.

## Related companies

- [Vernal Biosciences](/companies/vernal) (mRNA Manufacturing, Lipid Nanoparticle (LNP) Formulation) — [Compare](/compare/northernrna/vernal)
- [Hongene Biotech Corporation](/companies/hongene) (mRNA Manufacturing, Lipid Nanoparticle (LNP) Formulation) — [Compare](/compare/hongene/northernrna)
- [4basebio](/companies/4basebio) (mRNA Manufacturing, Lipid Nanoparticle (LNP) Formulation) — [Compare](/compare/4basebio/northernrna)
- [Fujifilm Pharmaceuticals U.S.A., Inc](/companies/fujifilmpharma) (mRNA Manufacturing, Lipid Nanoparticle (LNP) Formulation) — [Compare](/compare/fujifilmpharma/northernrna)
- [Biopharma Technology LLC](/companies/btllc) (Formulation Development, Process Development) — [Compare](/compare/btllc/northernrna)
- [Samsung Biologics](/companies/samsungbiologics) (mRNA Manufacturing, Lipid Nanoparticle (LNP) Formulation) — [Compare](/compare/northernrna/samsungbiologics)
- [Aldevron](/companies/aldevron) (mRNA Manufacturing, Lipid Nanoparticle (LNP) Formulation) — [Compare](/compare/aldevron/northernrna)
- [Biomay AG](/companies/biomay) (mRNA Manufacturing, Lipid Nanoparticle (LNP) Formulation) — [Compare](/compare/biomay/northernrna)

_Profile last updated: 2026-10-26T07:03:54.484Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.