---
name: Onyx Scientific
slug: onyxipca
site: cdmo
website_domain: onyxipca.com
summary: Small molecule CDMO specialising in process chemistry, solid-state chemistry, and API manufacturing for Phase I–III and commercial supply. Licensed for commercial API production at its Sunderland, UK facility, with a second site in North Carolina, US. Headquartered in Sunderland, United Kingdom.
tagline: Experts in small molecule API development & manufacturing
founded_year: 
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: GB
tier2_domain_verified: false
updated_at: 2026-11-04T07:00:54.655Z
services_count: 7
modalities_count: 1
indications_count: 0
locations_count: 2
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# Onyx Scientific

Experts in small molecule API development & manufacturing

Listed on cdmo.directory.

## Summary

Small molecule CDMO specialising in process chemistry, solid-state chemistry, and API manufacturing for Phase I–III and commercial supply. Licensed for commercial API production at its Sunderland, UK facility, with a second site in North Carolina, US. Headquartered in Sunderland, United Kingdom.

## At a glance

- HQ country: GB

## Services

- CMC Regulatory Submission Support
- Process Development
- CMC Analytical Development
- Stability Testing & Storage
- API Synthesis & Manufacturing
- Small Molecule Development & Manufacturing
- Solid-State Chemistry & Polymorph Screening

## Modalities

- Small Molecule

## Locations

- Sunderland, Sunderland, United Kingdom
- North Carolina, North Carolina, United States

## Long description

Onyx Scientific is a small molecule CDMO focused on API development and manufacturing.

**Capabilities named on the site**
- Process research and development, including QBD/DoE and process validation
- Solid-state chemistry: salt and co-crystal screening, polymorphism, chiral resolution screening, crystallization development, and preformulation studies
- Analytical development and stability
- Non-GMP manufacture and GMP manufacture for Phase I–III API supply
- Commercial API manufacturing, with the UK facility licensed to manufacture commercial API

**Locations**
- Sunderland, UK
- North Carolina, US

**Client feedback**
Testimonials describe work spanning pre-clinical through process validation, nanomedicine ligand drug substances, a 500g non-GLP scale-up with route optimisation and salt/polymorph screening, and GMP API campaigns. Clients cite transparent quotes, regular communication, and strong chemistry and process teams.

Onyx also announced more than £1.5m of investment to expand commercial API manufacturing capacity at its UK facility.

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_Profile last updated: 2026-11-04T07:00:54.655Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.