---
name: PI Health Sciences
slug: pihealthsciences
site: both
website_domain: pihealthsciences.com
summary: Integrated CRDMO offering end-to-end drug discovery, development, and manufacturing services with AI-driven capabilities, process optimization, analytical expertise, and GMP/non-GMP scale-up across small molecules and complex chemistry. Headquartered in Italy, Italy.
tagline: Integrated CRDMO combining 80 years of chemistry expertise with AI-driven discovery, development, and manufacturing solutions.
founded_year: 1946
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: IT
tier2_domain_verified: false
updated_at: 2026-10-05T07:03:46.065Z
services_count: 17
modalities_count: 1
indications_count: 0
locations_count: 5
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# PI Health Sciences

Integrated CRDMO combining 80 years of chemistry expertise with AI-driven discovery, development, and manufacturing solutions.

Listed on cdmo.directory.

## Summary

Integrated CRDMO offering end-to-end drug discovery, development, and manufacturing services with AI-driven capabilities, process optimization, analytical expertise, and GMP/non-GMP scale-up across small molecules and complex chemistry. Headquartered in Italy, Italy.

## At a glance

- Founded: 1946
- HQ country: IT

## Services

- CMC Analytical Development
- Analytical Method Development & Validation
- Stability Testing & Storage
- Process Development
- API Synthesis & Manufacturing
- Small Molecule Development & Manufacturing
- Flow Chemistry & Continuous Manufacturing
- HPAPI Manufacturing (High-Potency)
- Medicinal Chemistry
- Computational & In-Silico Drug Discovery
- Discovery Research
- Preclinical In Vitro Studies
- GLP Toxicology
- In Vitro ADME / DMPK
- Translational Research
- Regulatory Affairs
- CMC Regulatory Submission Support

## Modalities

- Small Molecule

## Locations

- Headquarters, Italy, Europe, Italy
- R&D and Manufacturing, Hyderabad, Telangana, India
- R&D and Manufacturing, Panoli, Gujarat, India
- R&D and Manufacturing, Jaipur, Rajasthan, India
- R&D and Manufacturing, Ankleshwar, Gujarat, India

## Long description

## Overview

PI Health Sciences is a leading Contract Research, Development and Manufacturing Organization (CRDMO) providing integrated solutions from discovery through commercial manufacturing. A subsidiary of PI Industries (founded 1946), the organization combines 80 years of chemistry expertise with modern AI and computational capabilities.

## Discovery & Development Services

- **Integrated Drug Discovery (IDD):** Co-located teams delivering synthetic chemistry, medicinal chemistry, biology, and preclinical toxicology with AI/computational chemistry integration
- **Chemistry Services:** Molecular modeling, scaffold synthesis, impurity characterization, strategic IP evaluation, and route scouting
- **DMPK Services:** Drug metabolism and pharmacokinetics support
- **Preclinical Services:** Full preclinical toxicology and safety assessment
- **Process Development:** Discovery process chemistry, route scouting, process development, and process safety evaluation
- **Analytical Services:** Method development and validation, genotoxic impurity analysis, stability and forced degradation testing, potent compound analysis, trace metal testing, salt and polymorph screening

## Manufacturing & Scale-Up

- **GMP/Non-GMP Scale-Up:** Phase-appropriate development from preclinical through commercial scale
- **Manufacturing Services:** Preclinical, clinical, and commercial manufacturing capabilities
- **Process Safety:** Advanced safety evaluations, hazard identification and assessment, thermal stability analysis, dust explosion testing, and engineering controls implementation

## Enabling Technologies

- **Flow Chemistry:** Integrated flow chemistry services
- **Biocatalysis:** Integrated biocatalysis services
- **In Silico Genotoxicity:** Computational genotoxicity prediction
- **New Modalities:** PROTAC, LYTAC, molecular glues, AUTAC, and other targeted protein degradation (TPD) platforms

## Regulatory & Quality

- Global regulatory compliance expertise supporting discovery to market
- Project management with certified project managers, agile methodologies, and cloud-based collaboration
- High potency compound analysis capabilities

## Global Presence

R&D and manufacturing locations in Europe (Italy) and India (Hyderabad, Panoli, Jaipur, Ankleshwar), serving big pharma and biotech partners across the US, Europe, and Japan.

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_Profile last updated: 2026-10-05T07:03:46.065Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.