---
name: Synthego
slug: synthego
site: cdmo
website_domain: synthego.com
summary: Synthego manufactures GMP-grade CRISPR components and molecular biology reagents for clinical and research applications, with 19 INDs cleared and 200+ clinical sgRNA batches produced.
tagline: GMP CRISPR components and molecular biology solutions for clinical therapeutics and research.
founded_year: 
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: 
tier2_domain_verified: false
updated_at: 2026-10-02T00:04:27.202Z
services_count: 4
modalities_count: 2
indications_count: 0
locations_count: 0
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# Synthego

GMP CRISPR components and molecular biology solutions for clinical therapeutics and research.

Listed on cdmo.directory.

## Summary

Synthego manufactures GMP-grade CRISPR components and molecular biology reagents for clinical and research applications, with 19 INDs cleared and 200+ clinical sgRNA batches produced.

## Services

- Cell-Line Development
- Process Development
- CMC Analytical Development
- CMC Regulatory Submission Support

## Modalities

- Gene Therapy
- Cell Therapy

## Long description

Synthego is a biotechnology company specializing in CRISPR gene editing solutions and molecular diagnostics. The company operates dual business lines: research-grade products sold through catalog channels, and contract GMP manufacturing services for clinical-stage therapeutics.

**GMP Manufacturing & Clinical Services:**
- GMP gRNA (guide RNA) synthesis with demonstrated IND-enabling capability (19 INDs cleared)
- GMP CRISPR editors (SpCas9, AccuBase base editor, hfCas12Max) in protein and mRNA formats
- Custom nuclease manufacturing for clinical applications
- Regulatory expertise and IND submission support
- 200+ clinical sgRNA batches manufactured to date
- 40+ successful customer audits completed

**Research & Molecular Biology Products:**
- Synthetic gRNA and CRISPR nuclease research kits
- Cell-free protein expression systems
- Isothermal amplification (RPA) reagents and enzymes
- PCR, reverse transcription, and IVT enzymes
- Sample preparation and nucleic acid processing products
- CRISPR design and analysis tools (ICE platform)

**Applications & Modalities:**
- CRISPR gene editing (base editing, CAR-T cell therapy, iPSC engineering)
- Cell and gene therapy manufacturing support
- Molecular and clinical diagnostics workflows

The company serves both academic researchers and therapeutic developers, with particular strength in enabling early-stage CRISPR-based cell and gene therapy programs through GMP-compliant manufacturing and regulatory guidance.

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_Profile last updated: 2026-10-02T00:04:27.202Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.