---
name: Yapan Bio
slug: yapan-bio
site: cdmo
website_domain: yapanbio.com
summary: Yapan Bio provides integrated process development, characterization, and GMP manufacturing for vaccines, monoclonal antibodies, gene therapy, and viral vector-based biologics, with capabilities up to 1000L bioreactor scale and BSL-2+ containment. Headquartered in Hyderabad, India.
tagline: Collaborative partner in process development and GMP manufacturing of vaccines and biologics.
founded_year: 
employee_count_band: 
employee_count_label: 
parent_name: 
parent_slug: 
hq_country: IN
tier2_domain_verified: false
updated_at: 2026-08-20T00:02:37.882Z
services_count: 15
modalities_count: 4
indications_count: 0
locations_count: 3
review_signal_gate: closed
generated_by: BioBM Editorial AI
---

# Yapan Bio

Collaborative partner in process development and GMP manufacturing of vaccines and biologics.

Listed on cdmo.directory.

## Summary

Yapan Bio provides integrated process development, characterization, and GMP manufacturing for vaccines, monoclonal antibodies, gene therapy, and viral vector-based biologics, with capabilities up to 1000L bioreactor scale and BSL-2+ containment. Headquartered in Hyderabad, India.

## At a glance

- HQ country: IN

## Services

- Cell-Line Development
- Upstream Processing
- Downstream Processing
- CMC Analytical Development
- Stability Testing & Storage
- Process Development
- Biologics Development & Manufacturing
- Monoclonal Antibody (mAb) Manufacturing
- Vaccine Manufacturing
- Viral Vector Manufacturing
- Sterile Fill-Finish & Aseptic Manufacturing
- Lyophilization (Freeze Drying)
- Vial Filling
- Microbial Fermentation
- Recombinant Protein Manufacturing

## Modalities

- Vaccine
- Biologics (Monoclonal Antibodies)
- Gene Therapy
- AAV / Viral Vector Platform

## Locations

- 450 GMP Facility, Hyderabad, Telangana, India
- Process Development Facility, Hyderabad, Telangana, India
- 270 GMP Facility, Hyderabad, Telangana, India

## Long description

Yapan Bio is a contract development and manufacturing organization (CDMO) specializing in process development and GMP manufacturing of complex biologics and vaccines. The company offers integrated services spanning early-stage process development and scale-up, process characterization with design-of-experiments support, and GMP manufacturing for clinical studies.

## Core Capabilities

**Process Development:**
- Cell line development
- Upstream manufacturing optimization (mammalian cell culture, insect cell culture, microbial fermentation)
- Downstream processing including centrifugation, tangential flow filtration, depth filtration, and chromatography
- Analytical method development and qualification
- Stability studies

**GMP Manufacturing:**
- Cell and virus seed banking
- Bioreactor systems: rocker, stirred tank, and adherent cell bioreactors
- Up to 1000L stirred bioreactor scale with single-use disposable technologies
- Aseptic formulation, fill and finish (lyophilization and liquid in vials)
- Separate manufacturing suites for non-infectious and infectious organisms (BSL-2+ containment)

**Product Classes:**
Experience developing recombinant vaccines, monoclonal antibodies (mAb), gene therapy products, and viral and non-viral vector-based therapeutics for global biotechnology companies.

## Facilities

Yapan Bio operates three state-of-the-art facilities at Genome Valley, Hyderabad, India:
- **450 GMP Facility:** ~6,360 sq ft, 2 GMP suites, up to 200L bioreactor scale, BSL-2+ containment, Class A/B/C/D areas
- **Process Development Facility:** ~6,825 sq ft, 3 separate upstream suites, BSL-2 containment, downstream and analytical development labs
- **270 GMP Facility:** ~13,500 sq ft, 2 separate GMP manufacturing lines, up to 1000L bioreactor scale, BSL-2 containment, Class A/B/C/D areas

## Service Model

Flexible partnership structures including milestone-based or FTE/retainership arrangements. Additional support includes third-party CRO management, regulatory filing support, and client engagement with regulatory agencies (USFDA, EMEA).

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_Profile last updated: 2026-08-20T00:02:37.882Z. Profile facts may include AI-assisted enrichment._

Auto-generated by BioBM Editorial AI for machine-readable profile access.