Micromacinazione

Overview

Micromacinazione is a Swiss-based pharmaceutical CDMO headquartered in Monteggio, Switzerland, with a global presence through partnership with Microsize in Quakertown, Pennsylvania. The company specializes in particle engineering and micronization, leveraging over 50 years of technical expertise and operational infrastructure.

Core Services

Particle Engineering:

• Micronization for poorly soluble compounds to improve dissolution, absorption, and clinical performance
• Milling for size reduction and particle optimization
• Spray drying for powder formulation development

Complementary Processing:

• Classification: Dynamic cyclone classification for precise aerodynamic fractions, essential for pulmonary delivery
• Blending: Planetary mixing for uniform API-excipient dry powder blends
• Cryogenic processing: Liquid nitrogen cooling for thermolabile or ductile compounds
• Co-micronization: Simultaneous jet milling of API and functional excipient for particle-level interaction
• Conditioning: Controlled humidity and temperature exposure for amorphous surface stabilization

Analytics:

• Particle characterization
• Solid-state characterization

Product Categories

The company serves APIs/HPAPIs, excipients, controlled substances, and specialty chemicals across development and commercial scales.

Infrastructure & Capabilities

• One dedicated R&D laboratory
• Three fully GMP-inspected production buildings
• Processing capacity from gram-scale feasibility to large commercial batches
• High-containment expertise for potent and controlled substances
• Dual-source capability across Switzerland and USA for supply continuity
• Global integration within a wider network of strategic partners for equipment innovation and technical solutions

Differentiation

The company positions itself as a specialized particle engineering partner (not a generalist CDMO) built on three pillars: Science Vanguard, Partnership by Design, and Redundancy. The team brings decades of particle engineering expertise, with operational capacity among the largest in Europe.