Phosphorex

Drug Delivery Expertise

Phosphorex operates the Phosphorex Drug Delivery Engine, a specialized platform focused on bridging the gap between promising preclinical biology and clinical reality through advanced drug delivery system design. The company addresses critical challenges in potency, immunogenicity, biodistribution, and patient safety.

Core Capabilities

• Formulation Optimization: Tailored formulation design across non-viral drug delivery platforms
• Process Design & CMC: Scalable, commercializable process development with critical quality attribute control
• Analytical Expertise: Comprehensive analytical support for drug delivery systems
• Tech Transfer & Troubleshooting: Process optimization, scale-up support, and technical problem-solving
• Benchmarking & Screening: Rapid evaluation of multiple formulation systems to identify optimal candidates

Modality Focus

The company demonstrates particular expertise in lipid nanoparticle (LNP) formulations for gene-editing therapies and other advanced modalities, with demonstrated capability in small-scale batch production (mg to 85 mg scale) and support for preclinical efficacy studies in rodent models.