CDMOs working on Oligonucleotide
Oligonucleotide is an important modality used by sponsors to shortlist partners for specific delivery, regulatory, and execution needs. This page groups CDMO organizations working on Oligonucleotide, so you can quickly identify which teams align with your program priorities without having to scan unrelated profiles.
Use this listing as a starting point: open each profile to review scope, facility footprint, and public evidence that supports the listed capabilities. Because the directory is fit-first, the goal is not to crown one universal "best" provider, but to help you build a right-sized shortlist for your stage, geography, and quality expectations.
When you are ready to compare options, move to search and add filters for adjacent criteria such as modalities, indications, and claim status. Combining this modality view with those filters makes it easier to narrow quickly from discovery to outreach while keeping the process transparent and reproducible.
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Matching companies
- ADViRNA
ADViRNA provides oligonucleotide design, synthesis, and screening services with proprietary chemical modifications and conjugation technologies for therapeutic siRNA and ASO development.
- AM Chemicals LLC
AM Chemicals supplies universal solid supports and phosphoramidite reagents for oligonucleotide synthesis, and offers custom radiolabeling services for ¹⁴C, ³⁵S, and ³H oligonucleotides with optional GMP manufacturing.
- AXOlabs
Integrated CRO and CDMO specializing in nucleic acid therapeutics (ASOs, siRNA, sgRNA, aptamers) from lead identification through GMP manufacturing, with dual-site facilities in Petaluma, USA and Berlin, Germany.
- Ajinomoto Bio-Pharma Services
Ajinomoto Bio-Pharma Services is a global contract development and manufacturing organization (CDMO) dedicated to improving the health of humankind through adaptive solutions and responsive service.
- Almac Group
Global CDMO with 7,900+ employees across 18 facilities, offering integrated drug development and manufacturing services including analytical development, formulation, process development, fill-finish, and specialized chemistry capabilities.
- Argonaut Manufacturing Services
Argonaut is a sterile fill-finish CDMO specializing in isolator-based aseptic manufacturing for biologics, peptides, nucleic acids, lipid nanoparticles, gene therapies, and vaccines from preclinical through commercial scale, with FDA and Annex 1 compliance.
- Asymchem Laboratories
Asymchem is a CDMO providing integrated API synthesis, drug product development, and biologics manufacturing with specialized capabilities in peptides, oligonucleotides, highly potent compounds, and flow chemistry.
- BOC Sciences
BOC Sciences is a custom lab chemical supplier offering bulk compounds, custom synthesis, cGMP manufacturing, analytical services, and specialized drug delivery and bioconjugation platforms for pharmaceutical and biotechnology clients.
- BSP Pharmaceuticals
BSP Pharmaceuticals is a CDMO specializing in development and manufacturing of cytotoxic oncology drugs, ADCs, peptides, proteins, and lipid-based formulations from preclinical GLP through commercial supply.
- Bachem
Global leader in peptide and oligonucleotide development and manufacturing, offering GMP-compliant clinical and commercial supply from early research through commercial scale.
- BioVectra
North American CDMO specializing in clinical-to-commercial biologics, small molecules, HPAPIs, and bioreagents with 50+ years of microbial fermentation and complex chemistry expertise across cGMP facilities in Canada.
- Biospring
Global CDMO leader in nucleic acid manufacturing and analysis (mRNA, ASO, siRNA, guide RNA, oligonucleotides) with nearly three decades of expertise, GMP certification since 2007, and support for 9 commercial programs across all clinical phases.
- CDMO Network
CDMO Network is a biomanufacturing partner-routing platform that connects biotech sponsors with specialized CDMO partners across modalities, development stages, and geographies to reduce integration friction and accelerate program execution.
- CPC Scientific
CPC Scientific provides GMP peptide and oligonucleotide manufacturing for Phase I through commercial programs, plus custom synthesis and FTE services for research applications.
- ChemGenes
ChemGenes is a market leader in nucleic acid chemistry, specializing in the manufacturing of DNA and RNA synthesis reagents, amidites, CPG solid supports, and nucleosides.
- CordenPharma
Full-service CDMO offering cGMP development and manufacturing of APIs, lipid excipients, drug products, injectables, peptides, LNPs, oligonucleotides, and oral solid dose across 10 facilities in 6 countries with 3000+ employees.
- Dalton Pharma Services
Health Canada–approved and FDA-inspected cGMP contract manufacturer offering integrated drug discovery, development, and manufacturing services including custom synthesis, API production, formulation development, and sterile fill-finish for vials, syringes, and cartridges.
- Ella Biotech
Independent German custom oligonucleotide synthesis provider near Munich, serving research, diagnostics, and preclinical development. Offers siRNA, ASO gapmer, and TRImer oligos with HPLC and mass spectrometry QC under ISO 9001 and ISO 13485 certification.
- Fujifilm Pharmaceuticals U.S.A., Inc
CDMO specializing in liposome and lipid nanoparticle (LNP) formulation development and GMP manufacturing from bench to commercial scale, with mRNA process development and aseptic fill-finish capabilities.
- GBI Biomanufacturing
Full-service biologics CDMO offering integrated development and manufacturing services including cell banking, upstream/downstream processing, bioconjugation, aseptic fill-finish, and regulatory support for complex biopharmaceuticals.
- Global Biotech Laboratories
Global Biotech Laboratories is a peptide and oligonucleotide CDMO offering end-to-end contract development and manufacturing from route scouting through validated commercial supply, with cGMP and ICH Q7 compliance across manufacturing sites on three continents.
- HitGen Inc.
HitGen Inc. provides drug discovery services built on DNA-encoded library (DEL), fragment-based (FBDD/SBDD) and computational platforms for pharmaceutical and biotech clients. The company also offers oligonucleotide CDMO services and reports serving more than 600 clients globally.
- Hongene Biotech Corporation
Hongene is a vertically-integrated CDMO offering end-to-end oligonucleotide and mRNA manufacturing from raw materials to GMP drug product, with nearly 30 years of RNA-focused expertise and tonne-scale production capacity.
- LGC Biosearch Technologies
GMP-compliant manufacturer of custom oligos, qPCR probes, and diagnostic kits for infectious diseases, oncology, and prenatal testing; ISO 13485-certified for clinical and diagnostic markets.
- Maravai LifeSciences
Leading provider of nucleic acid products, custom enzymes, and bioprocess analytics supporting vaccine, therapeutic, and diagnostic development from discovery through commercialization, with mRNA CDMO services including proprietary CleanCap® capping technology.
- PharmaBlock
Leading provider of innovative chemistry products and services for pharmaceutical R&D and commercial manufacturing, with expertise in process development, GMP manufacturing, and low-carbon chemistry solutions.
- Pharmaron
Premier life science CRO and CDMO offering integrated R&D and manufacturing across drug discovery, preclinical, clinical development, and commercialization for small molecules, biologics, and cell & gene therapies. 25,000+ employees across China, US, and UK.
- Phosphorex
Phosphorex specializes in advanced drug delivery system design and optimization, offering formulation development, process design, analytical expertise, and tech transfer services for gene therapies, mRNA, and other complex therapeutics.
- Porton
Porton is a global CDMO offering integrated manufacturing and development services across small molecules, peptides, oligonucleotides, biologics, and conjugates with specialized capabilities in flow chemistry, biocatalysis, and advanced therapies.
- Singota Solutions
Bloomington-based CDMO specializing in aseptic filling of small-volume parenterals (vials, syringes, cartridges), formulation development, QC testing, and supply chain management with GMP-compliant operations.
- Sinopep-Allsino Biopharmaceutical Co., Ltd.
GMP peptide and oligonucleotide CDMO offering custom synthesis, NCE development, CMC manufacturing, and finished dosage form formulation services for therapeutic programs.
- Sophia CDMO
European CDMO specializing in microbial and precision fermentation up to 40,000 L across two integrated sites (Pamplona, Spain and Basel, Switzerland), with core strengths in E. coli expression, animal health biologics, probiotics, and complex CMC programs requiring scale-up discipline and impurity control.
- Stevanato Group
Leading global provider of integrated drug containment, drug delivery, and diagnostic solutions with 75+ years' experience in glass primary packaging, contract manufacturing, and analytical services across development, clinical, and commercial stages.
- Syngene International
Innovation-led CRDMO offering integrated scientific services from early discovery through commercial manufacturing, with cGMP-compliant facilities, 5,200+ scientists, and a new 50,000-liter single-use bioreactor capacity in the U.S.
- TriLink BioTechnologies
TriLink manufactures mRNA, oligonucleotides, and modified nucleotides with proprietary CleanCap® capping technology achieving >95% Cap1 efficiency, supported by in-house analytical method development and a 118,000 sq ft GMP-capable facility.
- Veranova
Global CDMO specializing in development and manufacturing of complex active pharmaceutical ingredients (APIs), with expertise in solid form sciences, process development, and specialty modalities including ADCs and controlled substances.
- atdbio
ATDBio provides custom oligonucleotide synthesis, purification, and analysis services for research, diagnostics, and therapeutic applications.
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